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Selected Publications on the anti-inflammatory activities of somatostatin and its analogues


       

Somatostatin (14 and 28) and cortistatin inhibit TNF-α release in sub-lethal endotoxemia and sepsis models

Landa et al (1995) Res Exp Med (Berl) 195:317-25
Sener et al (2005) Peptides 26:493-9
Gonzalez-Rey et al (2006). J Exp Med 203:563-71

Octreotide and cortistatin showed efficacy in rodent models of Inflammatory Bowel Disease

Eliakim et al (1993) Gut 34:264-9
Lamrani et al (1999) Alim Pharmacol &Ther 13:583-94
Gonzalez-Rey et al (2006) PNAS USA 103:4228-33

Octreotide and cortistatin showed efficacy in rodent models of RA

Kurnatowska et al (2000) Neuro Endocrinol Lett 21:121-6
Gonzalez-Rey et al (2007) Ann Rheum Dis 66:582
Imhof et al (2011) Arthritis Rheum

Vapreotide showed efficacy in Crohn’s disease patients

Cortot et al (1994) Gut 35:F285

Somatostatin and octreotide showed efficacy in psoriasis and psoriatic arthritis patients

Weber et al (1982) Arch Dermatol Res 272:31-6
Guilhou et al (1982) Arch Dermatol Res 274:249-57
Matucci-Cerinic M et al (1988) Int J Dermatol 27:56-8
Venier et al (1988) Arch Dermatol Res 280:S51-4
Camisa et al (1990) Cleveland Clin J Med 57:71-6